COATED IMPLANTABLE MEDICAL DEVICE

专利名称：COATED IMPLANTABLE MEDICAL DEVICE发明人：Brian L. Bates,Anthony O. Ragheb,Neal E.

Fearnot,Thomas G. Kozma,William D.Voorhees, III

申请号：US12902788申请日：20101012

公开号：US20110046723A1公开日：20110224

专利附图：

摘要：A coated implantable medical device includes a structure adapted for

introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary

tract; at least one coating layer posited on one surface of the structure; and at least onelayer of a bioactive material posited on at least a portion of the coating layer wherein thecoating layer provides for the controlled release of the bioactive material from thecoating layer. In addition, at least one porous layer can be posited over the bioactivematerial layer wherein the porous layer includes a polymer and provides for thecontrolled release of the bioactive material therethrough. Preferably, the structure is acoronary stent. The porous layer includes a polymer applied preferably by vapor orplasma deposition and provides for a controlled release of the bioactive material. It isparticularly preferred that the polymer is a polyamide, parylene or a parylene derivative,which is deposited without solvents, heat or catalysts, and merely by condensation of amonomer vapor.

申请人：Brian L. Bates,Anthony O. Ragheb,Neal E. Fearnot,Thomas G. Kozma,William D.Voorhees, III

地址：Bloomington IN US,West Lafayette IN US,West Lafayette IN US,Canton GAUS,West Lafayette IN US

国籍：US,US,US,US,US

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