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METHOD FOR THE PREPARATION OF CITALOPRAM

2021-12-22 来源:尚佳旅游分享网
专利内容由知识产权出版社提供

专利名称:METHOD FOR THE PREPARATION OF

CITALOPRAM

发明人:PETERSEN, HANS,ROCK, MICHAEL,

HAROLD,SVANE, HENRIK

申请号:DK9900640申请日:19991122公开号:WO0013648A8公开日:20000511

摘要:Method for the preparation of citalopram comprising reaction of a compoundof Formula (IV) wherein R is halogen, or CF3-(CF2)n-SO2-, n being 0 to 8, with a cyanidesource in the presence of a palladium catalyst and a catalytic amount of Cu<+> orZn<2+>, or with Zn(CN)2 in the presence of a palladium catalyst.

申请人:H. LUNDBECK A/S,PETERSEN, HANS,ROCK, MICHAEL, HAROLD,SVANE, HENRIK

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